Medical Information & Literature — Context International
Service 05 / Medical Affairs

Medical Information
& Literature

Healthcare professionals, patients, and regulators ask questions your medical affairs function must answer — accurately, consistently, and within compliance boundaries. Behind every compliant response is an operation built on structured processes, trained personnel, and maintained knowledge libraries.

MI
Medical information — 24h standard response time
SLR
Systematic literature review — PRISMA compliant
SMPC
Label-aligned medical communication
PubMed Embase Cochrane ALL RECORDS IDENTIFIED n = database total Title / Abstract screen SCREENED RECORDS Title relevance filter Full-text eligibility FULL-TEXT ASSESSED Eligibility criteria INCLUDED STUDIES Final corpus SLR Report Evidence Summary PV Signal Input PRISMA-COMPLIANT LITERATURE FLOW
Literature Surveillance

Our search methodology — structured and repeatable

01
Search Strategy Design
MeSH term mapping, keyword string construction, and database-specific syntax optimisation. Documented search strings with Boolean operators, field limitations, and reproducible methodology.
02
Screening & Eligibility
Dual independent screening of titles and abstracts against pre-defined PICO(S) criteria. Full-text assessment for retained records with documented exclusion reasons per PRISMA guidelines.
03
Data Extraction
Structured extraction of study characteristics, patient populations, interventions, comparators, and outcomes into standardised templates. Quality assessment using validated tools (Cochrane RoB, GRADE).
04
Evidence Synthesis
Narrative synthesis with appropriate evidence grading. Where data permits, quantitative synthesis including meta-analytic methods with heterogeneity assessment and subgroup analysis.
Service Areas

Two disciplines. One integrated medical information function.

Medical Information
Enquiry Management
Managing unsolicited medical information requests from healthcare professionals — accurately, compliantly, and within commitment timelines. Every response grounded in approved product information with full documentation of enquiry and response.
  • HCP and patient enquiry intake and triage
  • Standard response document (SRD) library management
  • Off-label enquiry handling within regulatory constraints
  • Adverse event and product complaint identification and handoff
  • Medical information reporting and trending
  • Training on approved product claims and label limitations
Literature Operations
Systematic Review & Monitoring
Rigorous, PRISMA-compliant literature programmes — from ongoing surveillance for PV signal detection through comprehensive systematic reviews supporting regulatory submissions and medical education materials.
  • Ongoing literature monitoring — PubMed, Embase, WHO databases
  • Weekly surveillance reports with newly identified publications
  • Systematic literature reviews (SLR) — PICOS-defined
  • Evidence gap analysis for regulatory submission planning
  • Literature search strategy documentation and audit trail
  • Publication tracking and competitive intelligence
Source databases

Where our literature surveillance operates

P
PubMed / MEDLINE
Biomedical primary
E
Embase
European focus, drug safety
C
Cochrane Library
Systematic reviews, RCTs
W
WHO ICSR Database
VigiBase — PV signal detection
C
ClinicalTrials.gov
Trial registries — ongoing studies
S
Scopus
Citation database — broad coverage
W
Web of Science
Citation indexing — impact factors
R
Regional Databases
Middle East & Asian literature

Scientific rigour

A medical information response is only as reliable as the evidence search that produced it. We do not take shortcuts in the literature.

Medical Information Process

The MI enquiry journey — from contact to response

R
Receipt
Enquiry received via call, email, or web form — logged with HCP details and question verbatim
C
Classification
Enquiry triaged — on-label, off-label, AE/complaint identification, urgency level assigned
S
Search & Identify
SRD library searched. If no SRD match, literature search conducted and response drafted
R
Review & Approve
Medical review of response for accuracy, completeness, and compliance with label
D
Dispatch & Document
Response sent within commitment SLA. Full enquiry record archived for audit trail

Building your medical information function in the GCC?

Whether you need an outsourced MI call-handling service, an ongoing literature monitoring programme, or a comprehensive systematic review — we provide the scientific and operational capacity you need.

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